Making headlines for her budding romance with rocker John Cougar Mellencamp, Meg Ryan was spotted tending to her motherly duties during a New York City outing on Wednesday morning (January 5).

The "Sleepless In Seattle" actress dutifully held daughter Daisy True's hand as she escorted her little girl off to the local schoolhouse for the day's lessons.

She’s always up for a good time, and earlier today (May 17) Meg Ryan was spotted at the “Countdown to Zero” premiere at the 2010 Cannes Film Festival.

Joined by Lawrence Bender, the “When Harry Met Sally” babe looked amazing as she posed for the paparazzi in front of the Palais des Festivals.

Making for quite the star-studded affair, a bevy of celebrities showed up for the taping of "CNN Heroes: An All-Star Tribute" at the Kodak Theatre in Hollywood on Saturday night (November 22).

Among those on hand for the event were Taylor Swift, Jessica Biel, Cameron Diaz, Kate Beckinsale, Selena Gomez, Salma Hayek and Meg Ryan, along with performances by John Legend and Alicia Keys.